Student Researchers' Society Topics
Biocompatibility testing of 3D printed metallic materials in vitro and in vivo
Supervisor: TÖRÖK, Orsolya
3D printing technology, also known as additive manufacturing, has become an increasingly widespread and widely used method. In addition to plastic materials, it is now possible to use metallic materials in 3D printing and offers a design platform for the innovation of new alloys for application-specific compositional modifications. With 3D printing technology, it is possible to print metal implants with complex shapes tailored to the patient's anatomy. In medical applications, the biological response of the host tissue depends on the structural and compositional properties of the implanted biomaterial.
In this research project, biocompatibility testing of materials for medical devices and implants using 3D printing technology will be performed in in vitro cell culture and in vivo small animal models. We mainly use technologies and methods used in basic research.
Investigation of the effects of extreme physical stress using biochemical and genetic methods on human samples
Supervisor: TÖRÖK, Orsolya
The physiological response to physical activity, including extreme physical exertion, shows considerable heterogeneity between individuals. The identification of physiological factors that determine the performance of elite athletes and soldiers has long been the subject of several research studies. Within elite athletes, it is known that the highly glycolytic metabolism of sprinters, the highly oxidative metabolism of endurance athletes and the highly anabolic metabolism of bodybuilders influence metabolism at rest and after exercise to exhaustion.
In the present research project, we measure the metabolomic response of volunteers exposed to extreme physical exercise, complemented by genetic studies, in order to identify factors that determine extreme endurance performance.
Simulation-based medical education in clinical skills practice
Supervisor: TÖRÖK, Orsolya
Simulation-based medical education is a worldwide method that is now integrated into both undergraduate and postgraduate medical education in many places. The aim of this research is to validate in practice innovative medical education tools, simulation systems and IT solutions supporting medical education, and to compare them with traditional methods and to objectively characterise their fidelity.
Application of 3D printed degradable polymers as implants
Supervisor: MARÓTI, Péter
Co-supervisor: KARDOS, Kinga
Investigation of 3D printed degradable polymers (PLGA, PCL) and/or polymer composites with the main purpose of use as medical devices, in particular implants.
Prior knowledge: basic biological and mechanical knowledge
Determine print accuracy/production load with Markforged MetalX printer
Supervisor: MARÓTI, Péter
Co-supervisor: TOLD, Roland
Accuracy check of printers according to the guidelines of ISO/ASTM 52902:2023, evaluation of the specificity of the slicing program. Markforged MetalX printer A2 with tool steel and copper materials.
Skills, prior knowledge: Basic mechanical
Development and testing of 3D printed special structures for the development of sensors made of conductive polymers
Supervisor: MARÓTI, Péter
Co-supervisor: Dr. PAÁRI-MOLNÁR, Emese
Development and testing of different structures for conductive ABS and TPU composites using 3D printing technology to optimise strain sensors for later preclinical applications such as prosthetic fittings or ulcer detection.
Skills, prior knowledge: Basic mechanical and electrical knowledge
Development and testing of artificial muscle
Supervisor: MARÓTI, Péter
Co-supervisor: Dr. PAÁRI-MOLNÁR, Emese
Development of a silicone-ethanol composite material coating. Testing of different woven materials and tubes for the realisation of artificial muscle. Measurement of the force exerted on the finished artificial muscle in the materials testing laboratory.
Skills, prior knowledge: Basic mechanical and electrical knowledge
Electrical and magnetic properties of 3D printed metallic materials
Supervisor: MARÓTI, Péter
Co-supervisor: TOLD, Roland
Investigation of the electrical (conductivity, signal transmission) and magnetic properties of metal containing 3D printed polymers (PLA, ABS), i.e. how the magnetic field affects the printing parameters and the properties of the final sample. The determination of these material properties is important for further preclinical, clinical applications such as orthotics, prosthetics.
Skills, prior knowledge: basic mechanical and electrical knowledge
Heatable container build for medical material testing
Supervisor: MARÓTI, Péter
Co-supervisor: TOLD, Roland
Construction of a heatable container and thermostat, in which the testing samples would be keep on body temperature during the test time (37 °C). The container shape needs to be compatible the Zwick/Roell test machines. And the heating circulation has to be isolate from the container, that the tank can be filled any material (salt solution, blood).
Skills, prior knowledge: Basic mechanical and electrical knowledge
Utilizing additive manufacturing for dental implant design
Supervisor: MARÓTI, Péter
Co-supervisor: KARDOS, Kinga
Designing dental implants utilizing the opportunities provided by additive manufacturing involves the creation and optimization of a 3D model. This process focuses on achieving precise fit and optimal performance, considering both biomedical and materials technology criteria.
Prior knowledge: basic knowledge of modelling and biology
Damage Control Thoracic Surgery: animal model
Supervisor: MOLNÁR, F. Tamás DSc PhD
Chest drainage and management of penetrating cardiac injury are the two main challenges of modern thoracic surgery for trauma. Affordability and quality of simulation are limiting the scope of skill labs covering these issues. Development and trest of hybrid approaches are in the centre of topics of the project.